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Intracellular and Plasma Trough Concentration and Pharmacogenetics of Telaprevir

PURPOSE: Triple therapy for HCV-1 infection consists in boceprevir or telaprevir, ribavirin and PEG-interferon. Telaprevir is a P-glycoprotein substrate and it is metabolized by CYP3A4/5. No data have been published on intracellular penetration of telaprevir. We determined peripheral blood mononucle...

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Main Authors:	Jessica Cusato (Author), Sarah Allegra (Author), Amedeo De Nicolò (Author), Lucio Boglione (Author), Giovanna Fatiguso (Author), Adnan Mohamed Abdi (Author), Giuseppe Cariti (Author), Giovanni Di Perri (Author), Antonio D'Avolio (Author)
Format:	Book
Published:	Frontiers Media S.A., 2015-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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