Development of a Pharmacokinetic Model Describing Neonatal Fc Receptor‐Mediated Recycling of HL2351, a Novel Hybrid Fc‐Fused Interleukin‐1 Receptor Antagonist, to Optimize Dosage Regimen

HL2351 (hIL‐1Ra‐hyFc) is a novel recombinant protein formed by the fusion of two human interleukin‐1 receptor antagonist components into one antibody‐derived fragment crystallizable portion. Although HL2351 has a pharmacological mechanism of action similar to that of anakinra as a commercialized bio...

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Main Authors: Lien Ngo (Author), Jaeseong Oh (Author), Anhye Kim (Author), Hyun‐moon Back (Author), Won‐ho Kang (Author), Jung‐woo Chae (Author), Hwi‐yeol Yun (Author), Howard Lee (Author)
Format: Book
Published: Wiley, 2020-10-01T00:00:00Z.
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Call Number: A1234.567
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