Anemonin Attenuates RANKL-Induced Osteoclastogenesis and Ameliorates LPS-Induced Inflammatory Bone Loss in Mice via Modulation of NFATc1

• Main Authors: Huanhuan Hou (Author), Qisheng Peng (Author), Shaoming Wang (Author), Yuxin Zhang (Author), Jinjin Cao (Author), Yuming Deng (Author), Yingjian Wang (Author), Wan-chun Sun (Author), Hong-bing Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoporosis is a metabolic bone disease characterized by insufficient osteoblastic function and/or excessive osteoclastic activity. One promising strategy for treating osteoporosis is inhibiting excessive osteoclast resorbing activity. Previous studies have revealed that anemonin (ANE), isolated fr...