Light-Decomposable Polymeric Micelles with Hypoxia-Enhanced Phototherapeutic Efficacy for Combating Metastatic Breast Cancer

• Main Authors: Yuanyuan Li (Author), Aiyang Tong (Author), Peiyuan Niu (Author), Wenjing Guo (Author), Yangye Jin (Author), Yi Hu (Author), Pei Tao (Author), Wenjun Miao (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxygen dependence and anabatic hypoxia are the major factors responsible for the poor outcome of photodynamic therapy (PDT) against cancer. Combining of PDT and hypoxia-activatable bioreductive therapy has achieved remarkably improved antitumor efficacy compared to single PDT modality. However, cont...