Association of HLA-A and HLA-B Alleles with Lamotrigine-Induced Cutaneous Adverse Drug Reactions in the Thai Population

• Main Authors: Napatrupron Koomdee (Author), Jirawat Pratoomwun (Author), Thawinee Jantararoungtong (Author), Voralaksana Theeramoke (Author), Wichittra Tassaneeyakul (Author), Jettanong Klaewsongkram (Author), Ticha Rerkpattanapipat (Author), Siwalee Santon (Author), Apichaya Puangpetch (Author), Utcharee Intusoma (Author), Therdpong Tempark (Author), Tayard Deesudchit (Author), Patompong Satapornpong (Author), Anannit Visudtibhan (Author), Chonlaphat Sukasem (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Lamotrigine (LTG) is commonly used for treatment of epilepsy and bipolar disorder. It is one of the common cause of cutaneous adverse drug reactions (CADR). Clinical symptoms of LTG-induced CADR range from maculopapular exanthema (MPE) to severe cutaneous adverse reactions (SCAR). This s...