Cepharanthine as an effective small cell lung cancer inhibitor: integrated insights from network pharmacology, RNA sequencing, and experimental validation

BackgroundSmall cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options and poor prognosis, underscoring the need for new therapeutic agents.MethodsA library of 640 natural products was screened for anti-proliferative activity in SCLC cells. The effects of Cepharanthine (C...

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Main Authors: Fengyun Zhao (Author), Zhaowei Ding (Author), Mengting Chen (Author), Mingfang Ji (Author), Fugui Li (Author)
Format: Book
Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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