Active matrix metalloprotease-9 is associated with the collagen capsule surrounding the Madurella mycetomatis grain in mycetoma.

• Main Authors: Kirsten Geneugelijk (Author), Wendy Kloezen (Author), Ahmed H Fahal (Author), Wendy W J van de Sande (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Madurella mycetomatis is the main causative organism of eumycetoma, a persistent, progressive granulomatous infection. After subcutaneous inoculation M. mycetomatis organizes itself in grains inside a granuloma with excessive collagen accumulation surrounding it. This could be contributing to treatm...