Predicting drug response of tumors from integrated genomic profiles by deep neural networks

• Main Authors: Yu-Chiao Chiu (Author), Hung-I Harry Chen (Author), Tinghe Zhang (Author), Songyao Zhang (Author), Aparna Gorthi (Author), Li-Ju Wang (Author), Yufei Huang (Author), Yidong Chen (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human cancer cell lines to a wide collection of anti-ca...