Predicting drug response of tumors from integrated genomic profiles by deep neural networks

• Hoofdauteurs: Yu-Chiao Chiu (Auteur), Hung-I Harry Chen (Auteur), Tinghe Zhang (Auteur), Songyao Zhang (Auteur), Aparna Gorthi (Auteur), Li-Ju Wang (Auteur), Yufei Huang (Auteur), Yidong Chen (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human cancer cell lines to a wide collection of anti-ca...