Endogenous Derivatives of Linoleic Acid and their Stable Analogs Are Potential Pain Mediators

• Main Authors: Joshua J. Wheeler (Author), Anthony F. Domenichiello (Author), Jennifer R. Jensen (Author), Gregory S. Keyes (Author), Kristen M. Maiden (Author), John M. Davis (Author), Christopher E. Ramsden (Author), Santosh K. Mishra (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Psoriasis is characterized by intense pruritus, with a subset of individuals with psoriasis experiencing thermal hypersensitivity. However, the pathophysiology of thermal hypersensitivity in psoriasis and other skin conditions remains enigmatic. Linoleic acid is an omega-6 fatty acid that is concent...