Population Pharmacokinetics of Palbociclib in a Real-World Situation

• Main Authors: Bernard Royer (Author), Courèche Kaderbhaï (Author), Jean-David Fumet (Author), Audrey Hennequin (Author), Isabelle Desmoulins (Author), Sylvain Ladoire (Author), Siavoshe Ayati (Author), Didier Mayeur (Author), Sivia Ilie (Author), Antonin Schmitt (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Palbociclib is an oral cyclin-dependent kinase inhibitor that is used in combination with aromatase inhibitors in the treatment of postmenopausal women with metastatic breast cancer. Its metabolism profile is associated with an important interpatient variability. We performed a population pharmacoki...