The Hippo Coactivator TAZ Exacerbates Cisplatin-Induced Acute Renal Injury

• Main Authors: Xian Xue (Author), Xingwen Zhu (Author), Lu Zhou (Author), Xiaoli Sun (Author), Mengru Gu (Author), Yan Liang (Author), Mengzhu Tan (Author), Qing Hou (Author), Sudan Wang (Author), Chunsun Dai (Author)
• Format: Book
• Published: Karger Publishers, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Transcriptional coactivator with PDZ-binding motif (TAZ), a Hippo signaling pathway effector, maintains the balance of cell proliferation, differentiation, and death. However, the role of TAZ in tubular cell survival and acute kidney injury (AKI) remains largely unknown. Methods: We us...