The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice

• Main Authors: Anak A. S. S. K. Dharmapatni (Author), Melissa D. Cantley (Author), Victor Marino (Author), Egon Perilli (Author), Tania N. Crotti (Author), Malcolm D. Smith (Author), David R. Haynes (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To investigate the effect of Embelin, an inhibitor of X-Linked Inhibitor of Apoptosis Protein (XIAP), on inflammation and bone erosion in a collagen antibody induced arthritis (CAIA) in mice. Methods. Four groups of mice (n=6 per group) were allocated: CAIA untreated mice, CAIA treated wi...