Plug-and-play nucleic acid-mediated multimerization of biparatopic nanobodies for molecular imaging

• Main Authors: Laura Teodori (Author), Sarah K. Ochoa (Author), Marjan Omer (Author), Veronica L. Andersen (Author), Pernille Bech (Author), Junyi Su (Author), Jessica Bridoux (Author), Jesper S. Nielsen (Author), Mathias B. Bertelsen (Author), Sophie Hernot (Author), Kurt V. Gothelf (Author), Jørgen Kjems (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In cancer molecular imaging, selecting binders with high specificity and affinity for biomarkers is paramount for achieving high-contrast imaging within clinical time frames. Nanobodies have emerged as potent candidates, surpassing antibodies in pre-clinical imaging due to their convenient productio...