Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases

• Main Authors: Ena Tokiyoshi (Author), Mikio Watanabe (Author), Naoya Inoue (Author), Yoh Hidaka (Author), Yoshinori Iwatani (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The microRNA (miRNA) biogenesis pathway is regulated by specific proteins and enzymes, including Dicer, Drosha, DGCR8, Exportin 5 and the Argonaute (AGO) family. In this study, we investigated the AGO family, which is the primary component of RISC (RNA-induced silencing complex) and directly binds t...