Gene Therapy for Neuropathic Pain through siRNA-IRF5 Gene Delivery with Homing Peptides to Microglia
Astrocyte- and microglia-targeting peptides were identified and isolated using phage display technology. A series of procedures, including three cycles of both in vivo and in vitro biopanning, was performed separately in astrocytes and in M1 or M2 microglia, yielding 50-58 phage plaques in each cell...
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Main Authors: | Tomoya Terashima (Author), Nobuhiro Ogawa (Author), Yuki Nakae (Author), Toshiyuki Sato (Author), Miwako Katagi (Author), Junko Okano (Author), Hiroshi Maegawa (Author), Hideto Kojima (Author) |
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Format: | Book |
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Elsevier,
2018-06-01T00:00:00Z.
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