Targeting extracellular nutrient dependencies of cancer cells

• Váldodahkkit: Javier Garcia-Bermudez (Dahkki), Robert T. Williams (Dahkki), Rohiverth Guarecuco (Dahkki), Kıvanç Birsoy (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2020-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background: Cancer cells rewire their metabolism to meet the energetic and biosynthetic demands of their high proliferation rates and environment. Metabolic reprogramming of cancer cells may result in strong dependencies on nutrients that could be exploited for therapy. While these dependencies may...