Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

• Автори: Narcisse V T Gandjui (Автор), Abdel J Njouendou (Автор), Eric N Gemeg (Автор), Fanny F Fombad (Автор), Manuel Ritter (Автор), Chi A Kien (Автор), Valerine C Chunda (Автор), Jerome Fru (Автор), Mathias E Esum (Автор), Marc P Hübner (Автор), Peter A Enyong (Автор), Achim Hoerauf (Автор), Samuel Wanji (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

<h4>Background</h4>Infections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration. Despite this effort, there is still an urgent need for understanding the parasite biology especially the mating behaviour and...