Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

• Main Authors: Narcisse V T Gandjui (Author), Abdel J Njouendou (Author), Eric N Gemeg (Author), Fanny F Fombad (Author), Manuel Ritter (Author), Chi A Kien (Author), Valerine C Chunda (Author), Jerome Fru (Author), Mathias E Esum (Author), Marc P Hübner (Author), Peter A Enyong (Author), Achim Hoerauf (Author), Samuel Wanji (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Infections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration. Despite this effort, there is still an urgent need for understanding the parasite biology especially the mating behaviour and...