Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus.

• Main Authors: Sergio P Alpuche-Lazcano (Author), James Saliba (Author), Vivian V Costa (Author), Gabriel H Campolina-Silva (Author), Fernanda M Marim (Author), Lucas S Ribeiro (Author), Volker Blank (Author), Andrew J Mouland (Author), Mauro M Teixeira (Author), Anne Gatignol (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital malformations of the brain of neonates. To date, ZIKV mechanism of infection and pathogenesis is not entirely understood and different studies on gene regulation of ZIKV-infected cells have identified a dysregu...