An α-Gal antigenic surrogate as a biomarker of treatment evaluation in Trypanosoma cruzi-infected children. A retrospective cohort study.

• Main Authors: Manuel Abal (Author), Virginia Balouz (Author), Rosana Lopez (Author), M Eugenia Giorgi (Author), Carla Marino (Author), Cintia V Cruz (Author), Jaime Altcheh (Author), Carlos A Buscaglia (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Proper evaluation of therapeutic responses in Chagas disease is hampered by the prolonged persistence of antibodies to Trypanosoma cruzi measured by conventional serological tests and by the lack of sensitivity of parasitological tests. Previous studies indicated that...