Role of AmpG in the resistance to β-lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target

• Main Authors: Roshan D'Souza (Author), Le Phuong Nguyen (Author), Naina A. Pinto (Author), Hyunsook Lee (Author), Thao Nguyen Vu (Author), Hoyoung Kim (Author), Hyun Soo Cho (Author), Dongeun Yong (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A complex cascade of genes, enzymes, and transcription factors regulates AmpC β-lactamase overexpression. We investigated the network of AmpC β-lactamase overexpression in Klebsiella aerogenes and identified the role of AmpG in resistance to β-lactam agents, including cephalospor...