Arf6 as a therapeutic target: Structure, mechanism, and inhibitors

• Principais autores: Dejuan Sun (Autor), Yuanyuan Guo (Autor), Piyu Tang (Autor), Hua Li (Autor), Lixia Chen (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2023-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

ADP-ribosylation factor 6 (Arf6), a small G-protein of the Ras superfamily, plays pivotal roles in multiple cellular events, including exocytosis, endocytosis, actin remodeling, plasma membrane reorganization and vesicular transport. Arf6 regulates the progression of cancer through the activation of...