Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway

• Үндсэн зохиолчид: Soodeh Rajabi (Зохиогч), Hamid Najafipour (Зохиогч), Saeideh Jafarinejad Farsangi (Зохиогч), Siyavash Joukar (Зохиогч), Ahmad Beik (Зохиогч), Maryam Iranpour (Зохиогч), Zeinab Kordestani (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2020-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Pulmonary artery hypertension (PAH) is a vascular disease in the lung characterized by elevated pulmonary arterial pressure (PAP). Many miRNAs play a role in the pathophysiology of PAH. Perillyle alcohol (PA) and Quercetin (QS) are plant derivatives with antioxidant and anti-prol...