Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum

• Main Authors: Gayatri Panda (Author), Neha Mishra (Author), Disha Sharma (Author), Rintu Kutum (Author), Rahul C. Bhoyar (Author), Abhinav Jain (Author), Mohamed Imran (Author), Vigneshwar Senthilvel (Author), Mohit Kumar Divakar (Author), Anushree Mishra (Author), Parth Garg (Author), Priyanka Banerjee (Author), Sridhar Sivasubbu (Author), Vinod Scaria (Author), Arjun Ray (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

India confines more than 17% of the world's population and has a diverse genetic makeup with several clinically relevant rare mutations belonging to many sub-group which are undervalued in global sequencing datasets like the 1000 Genome data (1KG) containing limited samples for Indian ethnicity...