Eosinophil-Derived Neurotoxin Is Elevated in Patients with Amyotrophic Lateral Sclerosis

• Main Authors: Guan-Ting Liu (Author), Chi-Shin Hwang (Author), Chia-Hung Hsieh (Author), Chih-Hao Lu (Author), Sunny Li-Yun Chang (Author), Jin-Ching Lee (Author), Chien-Fu Huang (Author), Hao-Teng Chang (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objectives. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons in the brainstem, motor cortex, and spinal cord. Oxidative stress and neuroinflammation have been implicated in the pathophysiology of ALS. Members of the...