Delivery of Cell-Specific Aptamers to the Arterial Wall with an Occlusion Perfusion Catheter

• Main Authors: Ofonime Udofot (Author), Li-Hsien Lin (Author), William H. Thiel (Author), Megan Erwin (Author), Emily Turner (Author), Francis J. Miller, Jr (Author), Paloma H. Giangrande (Author), Saami K. Yazdani (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current strategies to prevent restenosis following endovascular treatment include the local delivery of anti-proliferative agents to inhibit vascular smooth muscle cell (VSMC) proliferation and migration. These agents, not specific to VSMCs, are deposited on the luminal surface and therefore target...