Pharmacological inhibition of Src family kinases attenuates hyperuricemic nephropathy

• Main Authors: Chongxiang Xiong (Author), Jin Deng (Author), Xin Wang (Author), Qidi Hou (Author), Shougang Zhuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperuricemia is an independent risk factor for chronic kidney disease and contributes to renal fibrosis. This study aims to investigate the effect of Src family kinase (SFK) inhibition on the development of hyperuricemic nephropathy (HN) and the mechanisms involved. In a rat model of HN, feeding ra...