Interleukin-19 Is a Negative Regulator of Innate Immunity and Critical for Colonic Protection

• Main Authors: Yasu-Taka Azuma (Author), Yukiko Matsuo (Author), Hidemitsu Nakajima (Author), George D. Yancopoulos (Author), David M. Valenzuela (Author), Andrew J. Murphy (Author), Margaret Karow (Author), Tadayoshi Takeuchi (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cytokine, interleukin (IL)-19, is a member of the IL-10 family that includes IL-20, IL-22, IL-24, and IL-26. Recent studies have shown that IL-19 is produced by keratinocytes, epithelial cells, macrophages, and B-cells. Little is known about the exact biological role of IL-19 in immunological re...