Polysulfide protects midbrain dopaminergic neurons from MPP+-induced degeneration via enhancement of glutathione biosynthesis

• Κύριοι συγγραφείς: Shuhei Takahashi (Συγγραφέας), Akinori Hisatsune (Συγγραφέας), Yuki Kurauchi (Συγγραφέας), Takahiro Seki (Συγγραφέας), Hiroshi Katsuki (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2018-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Polysulfides are endogenous sulfur-containing molecular species that may regulate various cellular functions. Here we examined the effect of polysulfides exogenously applied to rat midbrain slice cultures, to address their potential neuroprotective actions. Na2S3 at concentrations of 10 μM or higher...