Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation

• Asıl Yazarlar: Tatiana Takiishi (Yazar), Peng Xiao (Yazar), Marie Franchimont (Yazar), Eduardo H. Gilglioni (Yazar), Erick N. Arroba (Yazar), Esteban N. Gurzov (Yazar), Mathieu JM. Bertrand (Yazar), Alessandra K. Cardozo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2023-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objectives: Type 1 diabetes (T1D) is caused by progressive immune-mediated loss of insulin-producing β-cells. Inflammation is detrimental to β-cell function and survival, moreover, both apoptosis and necrosis have been implicated as mechanisms of β-cell loss in T1D. The receptor interacting serine/t...