Allergic Reactions at Enzyme Replacement Therapy in Children with Mucopolysaccharidosis Type II

• Main Authors: Julia G. Levina (Author), Nato D. Vashakmadze (Author), Leyla S. Namazova-Baranova (Author), Elena A. Vishneva (Author), Natalia V. Zhurkova (Author), Kamilla E. Efendieva (Author), Anna A. Alekseeva (Author), Vera G. Kalugina (Author)
• Format: Book
• Published: "Paediatrician" Publishers LLC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is rare hereditary disease caused by changes in the IDS gene and associated deficiency of lysosomal enzyme iduronate-2-sulfatase (I2S). The main treatment scheme for children with MPS II is enzyme replacement therapy (ERT) with recombinant huma...