Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway

• Main Authors: Heng Cai (Author), Lin-Yan Huang (Author), Rui Hong (Author), Jin-Xiu Song (Author), Xin-Jian Guo (Author), Wei Zhou (Author), Zhao-Li Hu (Author), Wan Wang (Author), Yan-Ling Wang (Author), Jian-Gang Shen (Author), Su-Hua Qi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the present study, we isolated and characterized novel ELNs from Momordica charantia (MC) and investigated their neuroprote...