Determination of Gastric Water Emptying in Fasted and Fed State Conditions Using a Compression-Coated Tablet and Salivary Caffeine Kinetics

• Main Authors: Theodora Tzakri (Author), Lara Rehenbrock (Author), Stefan Senekowitsch (Author), Adrian Rump (Author), Philipp Schick (Author), Julius Krause (Author), Marie-Luise Kromrey (Author), Michael Grimm (Author), Werner Weitschies (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Because of the importance of gastric emptying for pharmacokinetics, numerous methods have been developed for its determination. One of the methods is the salivary tracer technique, which utilizes an ice capsule containing caffeine as a salivary tracer. Despite the ice capsule's advantage in lab...