Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics

• Main Authors: Erdem Yildiz (Author), Anselm J. Gadenstaetter (Author), Matthias Gerlitz (Author), Lukas D. Landegger (Author), Rudolfs Liepins (Author), Michael Nieratschker (Author), Rudolf Glueckert (Author), Hinrich Staecker (Author), Clemens Honeder (Author), Christoph Arnoldner (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hearing impairment is the most common sensory disorder in humans, and yet hardly any medications are licensed for the treatment of inner ear pathologies. Intricate pharmacokinetic examinations to better understand drug distribution within this complex organ could facilitate the development of novel...