Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors

• Auteurs principaux: Agnieszka M. Jurga (Auteur), Ewelina Rojewska (Auteur), Wioletta Makuch (Auteur), Joanna Mika (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Context: Accumulating evidence has demonstrated that Toll-like receptors (TLRs), especially TLR4 localized on microglia/macrophages, may play a significant role in nociception. Objective: We examine the role of TLR4 in a neuropathic pain model. Using behavioural/biochemical methods, we examined the...