Focused Ultrasound-Mediated Disruption of the Blood-Brain Barrier for AAV9 Delivery in a Mouse Model of Huntington's Disease

Focused Ultrasound-Mediated Disruption of the Blood-Brain Barrier for AAV9 Delivery in a Mouse Model of Huntington's Disease

Huntington's disease (HD) is a monogenic neurodegenerative disorder caused by a cytosine-adenine-guanine (CAG) trinucleotide repeat expansion in the <i>HTT</i> gene. There are no cures for HD, but the genetic basis of this disorder makes gene therapy a viable approach. Adeno-associa...

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Main Authors: Bernie S. Owusu-Yaw (Author), Yongzhi Zhang (Author), Lilyan Garrett (Author), Alvin Yao (Author), Kai Shing (Author), Ana Rita Batista (Author), Miguel Sena-Esteves (Author), Jaymin Upadhyay (Author), Kimberly Kegel-Gleason (Author), Nick Todd (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
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