Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis

Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and...

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Main Authors: Morteza Abyadeh (Author), Fatemeh Heydarinejad (Author), Maliheh Khakpash (Author), Yaser Asefi (Author), Sakineh Shab-Bidar (Author)
Format: Book
Published: Taylor & Francis Group, 2020-04-01T00:00:00Z.
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100 1 0 |a Morteza Abyadeh  |e author 
700 1 0 |a Fatemeh Heydarinejad  |e author 
700 1 0 |a Maliheh Khakpash  |e author 
700 1 0 |a Yaser Asefi  |e author 
700 1 0 |a Sakineh Shab-Bidar  |e author 
245 0 0 |a Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis 
260 |b Taylor & Francis Group,   |c 2020-04-01T00:00:00Z. 
500 |a 1064-1955 
500 |a 1525-6065 
500 |a 10.1080/10641955.2020.1753068 
520 |a Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and in case of existing heterogeneity a random-effects model was applied. Results Association of ApoE polymorphism with the risk of developing PE was not statistically significant (OR = 0.86, 95% CI: 0.67-1.11; OR = 0.92, 95%CI: 0.73-1.15, respectively for ε2 and ε4). Conclusion ApoE polymorphism might not be associated with the risk of PE. 
546 |a EN 
690 |a apolipoprotein e 
690 |a polymorphism 
690 |a preeclampsia 
690 |a meta-analysis 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Hypertension in Pregnancy, Vol 39, Iss 2, Pp 196-202 (2020) 
787 0 |n http://dx.doi.org/10.1080/10641955.2020.1753068 
787 0 |n https://doaj.org/toc/1064-1955 
787 0 |n https://doaj.org/toc/1525-6065 
856 4 1 |u https://doaj.org/article/43d30b47288b4ee78d9a33e8d9bddb51  |z Connect to this object online.