Bispidine-amino acid conjugates act as a novel scaffold for the design of antivirals that block Japanese encephalitis virus replication.

• Main Authors: V Haridas (Author), Kullampalayam Shanmugam Rajgokul (Author), Sandhya Sadanandan (Author), Tanvi Agrawal (Author), Vats Sharvani (Author), M V S Gopalakrishna (Author), M B Bijesh (Author), Kanhaiya Lal Kumawat (Author), Anirban Basu (Author), Guruprasad R Medigeshi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Japanese encephalitis virus (JEV) is a major cause of viral encephalitis in South and South-East Asia. Lack of antivirals and non-availability of affordable vaccines in these endemic areas are a major setback in combating JEV and other closely related viruses such as West Nile virus and dengue virus...