Sustained and Long-Term Release of Doxorubicin from PLGA Nanoparticles for Eliciting Anti-Tumor Immune Responses

• Main Authors: Jeongrae Kim (Author), Yongwhan Choi (Author), Suah Yang (Author), Jaewan Lee (Author), Jiwoong Choi (Author), Yujeong Moon (Author), Jinseong Kim (Author), Nayeon Shim (Author), Hanhee Cho (Author), Man Kyu Shim (Author), Sangmin Jeon (Author), Dong-Kwon Lim (Author), Hong Yeol Yoon (Author), Kwangmeyung Kim (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunogenic cell death (ICD) is a powerful trigger eliciting strong immune responses against tumors. However, traditional chemoimmunotherapy (CIT) does not last long enough to induce sufficient ICD, and also does not guarantee the safety of chemotherapeutics. To overcome the disadvantages of the con...