Investigating the crucial roles of aliphatic tails in disulfide bond-linked docetaxel prodrug nanoassemblies

• Main Authors: Yuequan Wang (Author), Cong Luo (Author), Shuang Zhou (Author), Xinhui Wang (Author), Xuanbo Zhang (Author), Shumeng Li (Author), Shenwu Zhang (Author), Shuo Wang (Author), Bingjun Sun (Author), Zhonggui He (Author), Jin Sun (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disulfide bond-bridging strategy has been extensively utilized to construct tumor specificity-responsive aliphatic prodrug nanoparticles (PNPs) for precise cancer therapy. Yet, there is no research shedding light on the impacts of the saturation and cis-trans configuration of aliphatic tails on the...