Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.

• Main Authors: Aïssatou Diawara (Author), Carli M Halpenny (Author), Thomas S Churcher (Author), Charles Mwandawiro (Author), Jimmy Kihara (Author), Ray M Kaplan (Author), Thomas G Streit (Author), Youssef Idaghdour (Author), Marilyn E Scott (Author), Maria-Gloria Basáñez (Author), Roger K Prichard (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Albendazole (ABZ), a benzimidazole (BZ) anthelmintic (AH), is commonly used for treatment of soil-transmitted helminths (STHs). Its regular use increases the possibility that BZ resistance may develop, which, in veterinary nematodes is caused by single nucleotide polymorphisms (SNPs) in the β-tubuli...