Cardiovascular and Renal Effects of High Salt Diet in GDNF+/- Mice with Low Nephron Number

• Главные авторы: Julia Schlote (Автор), Agnes Schröder (Автор), Anke Dahlmann (Автор), Britta Karpe (Автор), Nada Cordasic (Автор), Christoph Daniel (Автор), Karl Friedrich Hilgers (Автор), Jens Titze (Автор), Kerstin Amann (Автор), Kerstin Benz (Автор)
• Формат: ‌
• Опубликовано: Karger Publishers, 2013-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Aims: To test the suggested association of low nephron number and later development of renal and cardiovascular disease we investigated the effects of high sodium diet in heterozygous GDNF+/- mice. Methods: Aged wild type and GDNF+/- mice were grouped together according to high sodium (HS, 4%) or lo...