Voriconazole injection may induce delayed methotrexate excretion: a case report and experimental study

• Príomhchruthaitheoirí: Daisuke Watahiki (Údar), Daisuke Saito (Údar), Naonori Nishida (Údar), Hiroyuki Tsuri (Údar), Keiko Nomura (Údar), Yuichi Adachi (Údar), Masato Taguchi (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: BMC, 2022-03-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Abstract Background We report a case of delayed excretion of methotrexate (MTX) in a pediatric patient on high-dose MTX therapy in response to a change in the concomitant dosage of voriconazole from oral to intravenous. As the intravenous, but not the oral formulation of voriconazole includes sulfob...