Methylation of the RASSF1A, RARβ2, and SEMA3B genes in epithelial breast and ovarian tumors, and in patients with polyneoplasia

• Main Authors: T. P. Kazubskaya (Author), V. I. Loginov (Author), D. S. Khodyrev (Author), V. D. Ermilova (Author), Yu. G. Payanidi (Author), N. V. Chkhikvadze (Author), V. Yu. Selchuk (Author), E. A. Braga (Author)
• Format: Book
• Published: ABV-press, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The methylation status of the tumor suppressor genes RASSF1A, RARβ2, and SEMA3B was studied in the samples of cancer and its histologically normal tissue of the breast and ovaries. The high rate of abnormal methylation of the CpG islet in the RASSF1A, RARβ2, and SEMA3B genes was found in the tumors...