Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification

IntroductionExposure to fine particulate matter (PM2.5) is known to be associated with cardiovascular diseases. Sesamin (Ses) is a natural phenolic compound found in sesame seeds and sesame oil. Ferroptosis is a novel mode of cell death characterised by iron-dependent lipid peroxidation. This study...

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Main Authors: Yadong Zhang (Author), Rui Wen (Author), Jingyi Ren (Author), Fan Zhang (Author), Huanting Pei (Author), Jinshi Zuo (Author), Yuxia Ma (Author)
Format: Book
Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
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