Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification

• Päätekijät: Yadong Zhang (Tekijä), Rui Wen (Tekijä), Jingyi Ren (Tekijä), Fan Zhang (Tekijä), Huanting Pei (Tekijä), Jinshi Zuo (Tekijä), Yuxia Ma (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

IntroductionExposure to fine particulate matter (PM2.5) is known to be associated with cardiovascular diseases. Sesamin (Ses) is a natural phenolic compound found in sesame seeds and sesame oil. Ferroptosis is a novel mode of cell death characterised by iron-dependent lipid peroxidation. This study...