Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from <i>Bothrops pictus</i> (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines

• Glavni autori: Dan E. Vivas-Ruiz (Autor), Paola Rosas (Autor), Alex Proleón (Autor), Daniel Torrejón (Autor), Fanny Lazo (Autor), Ana Belén Tenorio-Ricca (Autor), Francisco Guajardo (Autor), Cristopher Almarza (Autor), Víctor Andrades (Autor), Jessica Astorga (Autor), Daniel Oropesa (Autor), Jorge Toledo (Autor), María Jesús Vera (Autor), Jorge Martínez (Autor), Ramiro Araya-Maturana (Autor), Karen Dubois-Camacho (Autor), Marcela A. Hermoso (Autor), Valéria G. Alvarenga (Autor), Eladio Flores Sanchez (Autor), Armando Yarlequé (Autor), Luciana Souza Oliveira (Autor), Félix A. Urra (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

From the venom of the <i>Bothrops pictus</i> snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration. In this work, we characterize a novel P-III class snake venom metalloproteinase, called pictolysin-III (Pic-I...