A phase I COVID-19 vaccine trial among SARS-CoV-2 seronegative and seropositive individuals in Uganda utilizing a self-amplifying RNA vaccine platform: Screening and enrollment experiences

• Main Authors: Jonathan Kitonsa (Author), Onesmus Kamacooko (Author), Eugene Ruzagira (Author), Florence Nambaziira (Author), Andrew Abaasa (Author), Jennifer Serwanga (Author), Ben Gombe (Author), Jane Lunkuse (Author), Hadijah Naluyinda (Author), Naboth Tukamwesiga (Author), Tamara Namata (Author), Antony Kigozi (Author), Paddy Kafeero (Author), Vincent Basajja (Author), Sarah Joseph (Author), Benjamin F. Pierce (Author), Robin Shattock (Author), Pontiano Kaleebu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report the screening and enrollment process for a phase I vaccine trial in Masaka, Uganda that investigated the safety and immunogenicity of a self-amplifying SARS-CoV-2 RNA vaccine amongst individuals with and without antibodies to SARS-CoV-2. Participant screening and enrollment were conducted...