Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers

• প্রধান লেখক: Kanghee Jo (লেখক), Jae Min Cho (লেখক), Hyunjoo Lee (লেখক), Eun Kyung Kim (লেখক), Hong Chul Kim (লেখক), Hyeongmin Kim (লেখক), Jaehwi Lee (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2018-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

This study aimed to design phosphatidylcholine (PC)-based solid dispersion (SD) systems for enhancing the apparent aqueous solubility and dissolution of celecoxib (CLC), a selective cyclooxygenase-2 inhibitor with a highly hydrophobic property. Although PC-based dispersion formulations considerably...