VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes

• Main Authors: Alexandru Filippi (Author), Alina Constantin (Author), Nicoleta Alexandru (Author), Cristina Ana Mocanu (Author), Mihaela Loredana Vlad (Author), Ioana Madalina Fenyo (Author), Agneta Simionescu (Author), Dan Teodor Simionescu (Author), Ileana Manduteanu (Author), Adriana Georgescu (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The number and function of endothelial progenitor cells (EPCs) are reduced in diabetes, contributing to deteriorated vascular repair and the occurrence of cardiovascular complications. Here, we present the results of treating early diabetic dyslipidemic mice or dyslipidemic with disease-matched EPCs...