Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay

• Main Authors: Paul Scorer (Author), Marietta Scott (Author), Nicola Lawson (Author), Marianne J. Ratcliffe (Author), Craig Barker (Author), Marlon C. Rebelatto (Author), Jill Walker (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Several anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) therapies have shown encouraging safety and clinical activity in a variety of tumor types. A potential role for PD-L1 testing in identifying patients that are more likely to respond to tre...