Pharmacokinetics, pharmacodynamics, safety, and immunogenicity of Pelmeg®, a pegfilgrastim biosimilar in healthy subjects

• Asıl Yazarlar: Karsten Roth (Yazar), Dirk Lehnick (Yazar), Hendrik Wessels (Yazar), Josef Höfler (Yazar), Barbara Gastl (Yazar), Ruediger Jankowsky (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2019-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract A pharmacokinetics (PK)/pharmacodynamics (PD) study (EudraCT number 2015‐002966‐21) was conducted to investigate the biosimilarity of Pelmeg® (pegfilgrastim), a biosimilar to EU‐authorized Neulasta®, which is used in the clinic for prevention of chemotherapy‐induced neutropenia. The single‐...